Most pipelines require a unique way to organize samples, but looper subscribes to standard Portable Encapsulated Project (PEP) format. PEP is a standardized way to represent metadata about your project and each of its samples. If you follow this format, then your project can be read not only by looper, but also by other software, like the pepr R package, or the peppy python package. You should read the instructions on how to create a PEP to use with looper.
So, the first thing you should do is follow the instructions for how to make a PEP. Once you've have a basic PEP created, the next section shows you how to add looper-specific configuration to the PEP config file, or you can jump ahead to linking a project to a pipeline.